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Human Immune System Quiz

Try out this Human Immune System quiz to test your knowledge. Human Immune System trivia explores the remarkable defenses that help the body recognize and respond to germs, injuries, and other threats.

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15 questions

~3 min to finish

Easy to hard difficulty

450 pts max score

  1. Question 1 · Hard · 40 pts

    On nearly all nucleated human cells, which class of MHC molecule is present?

  2. Question 2 · Hard · 40 pts

    Professional antigen-presenting cells mainly express which class of MHC molecule?

  3. Question 3 · Hard · 40 pts

    In which organ do T cells undergo both positive and negative selection?

  4. Question 4 · Hard · 40 pts

    Which pair of genes is essential for V(D)J recombination in developing lymphocytes?

  5. Question 5 · Hard · 40 pts

    Activated B cells use what process to improve antibody affinity by introducing variation?

  6. Question 6 · Hard · 40 pts

    Which mechanism changes an antibody's isotype while leaving antigen specificity unchanged?

  7. Question 7 · Hard · 40 pts

    During many antibody responses, what structures form in secondary lymphoid organs?

  8. Question 8 · Hard · 40 pts

    What is the name of the process that raises the average binding strength of antibodies over time?

  9. Question 9 · Hard · 40 pts

    What is the pore-forming terminal structure of the complement cascade called?

  10. Question 10 · Hard · 40 pts

    Cytotoxic lymphocytes rely on which molecule to help deliver granzymes into target cells?

  11. Question 11 · Easy · 10 pts

    Which immune organ lies in the upper chest behind the sternum?

  12. Question 12 · Easy · 10 pts

    What organ is found in the left upper part of the abdomen?

  13. Question 13 · Easy · 10 pts

    Which cells produce antibodies?

  14. Question 14 · Easy · 10 pts

    CD4 is commonly associated with which type of T cell?

  15. Question 15 · Easy · 10 pts

    What are allergy shots a form of?